Enko’s target-based approach, and our ability to develop deep biochemical and structural understanding of these targets, allows us to leverage Structure-Based Design principles in our programs.
Protein structures are atomic-scale maps we use to understand how our molecules interact with target proteins to change their function. We use this understanding to optimize our molecules using Structure-Based Design; an approach where we leverage physics-based modeling techniques and simulations to effectively identify the parts of a molecule which can be altered to improve its commercial characteristics. This power enables us to dial-in safety, selectivity, potency, and other properties that are essential to delivering safe, effective, and sustainable solutions to growers.